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Rabbit Anti-KIF15/Gold Conjugated antibody (bs-10693R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-10693R-Gold
英文名稱 Rabbit Anti-KIF15/Gold Conjugated antibody
中文名稱 膠體金標記的驅動蛋白家族成員15抗體
別    名 Kinesin like protein 7; KLP2; FLJ25667; HKLP2; Kinesin family member 15; Kinesin like protein 2; Kinesin like protein 7; Kinesin like protein KIF15; KLP2; KNSL7; Linesin like 7; NY BR 62; NYBR62; Serologically defined breast cancer antigen NY BR 62; Serologically defined breast cancer antigen NYBR62; FLJ25667; KIF15_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  細胞骨架  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Horse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 160kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF15
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
KIF15 belongs to the kinesin-like protein family and contains 1 kinesin-motor domain. KIF15 is the plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.

Function:
Plus-end directed kinesin-like motor enzyme involved inmitotic spindle assembly.

Subunit:
Interacts with MKI67 and TPX2.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton, spindle.Note=Detected during the interphase in the cytoplasm as finelypunctuate pattern and irregularly shaped dots. Detected duringmitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis.Localizes at the central spindle at anaphase.Localizes at the sites of invaginating cell membranes, a positionthat corresponds to the location of the contractile actomyosin ringof dividing cells. Colocalizes with actin ininterphase. Colocalizes in dendrites and in growthcone of axons with microtubules.

Tissue Specificity:
Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis.

Similarity:
Belongs to the kinesin-like protein family. KLP2subfamily.
Contains 1 kinesin-motor domain.

Database links:

Entrez Gene: 56992 Human

Entrez Gene: 209737 Mouse

Entrez Gene: 353302 Rat

SwissProt: Q9NS87 Human

SwissProt: Q6P9L6 Mouse

SwissProt: Q7TSP2 Rat

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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