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Rabbit Anti-KIAA2022/Gold Conjugated antibody (bs-17033R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-17033R-Gold
英文名稱 Rabbit Anti-KIAA2022/Gold Conjugated antibody
中文名稱 膠體金標記的KIAA2022蛋白抗體
別    名 Protein KIAA2022; expressed sequence C77370; K2022_HUMAN; Kiaa2022; RP11-130N24.1; RP23-35L3.1; Uncharacterized protein KIAA2022.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  免疫學  發(fā)育生物學  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Horse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 167kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Protein KIAA2022
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
KIAA2022 is a 1,516 amino acid protein that is highly expressed in both adult and fetal brain and is encoded by a gene which maps to human chromosome X. Chromosomal aberrations involving the KIAA2022 gene are associate with the development of severe mental retardation, suggesting a role for KIAA2022 in normal brain development and function. Human chromosome X, on which the KIAA2022 gene is localized, contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

Tissue Specificity:
Highly expressed in fetal and adult brain, predominantly in the cerebral cortex and the cerebellum. Also expressed in other tissues but to a lesser extent.

DISEASE:
Note=A chromosomal aberration involving KIAA2022 is found in 2 patients with severe mental retardation (MR). Pericentric inversion inv(X)(p22.3;q13.2). The Xq13 breakpoint lies within a predicted intron of KIAA2022 gene. KIAA2022 protein is no longer expressed in these patients lymphocytes.

Database links:

Entrez Gene: 340533 Human

Omim: 300524 Human

SwissProt: Q5QGS0 Human

Unigene: 124128 Human 

Entrez Gene: 100173017 Orangutan

Entrez Gene: 100155718 Pig

Entrez Gene: 716288 Rhesus monkey

Omim: 607359 Human

SwissProt: Q8N163 Human

SwissProt: Q8VDP4 Mouse

SwissProt: Q5R8S0 Orangutan

Unigene: 433722 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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