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Rabbit Anti-Oxytocin R/BF488 Conjugated antibody (bs-1314R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1314R-BF488
英文名稱(chēng) Rabbit Anti-Oxytocin R/BF488 Conjugated antibody
中文名稱(chēng) BF488標(biāo)記的催產(chǎn)素受體(縮宮素受體)抗體
別    名 Oxytocin R; OT R; OT-R; OTR 1; OTR; OTR1; OXT R; OXTR; Oxytocin receptor; OXYR_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  生長(zhǎng)因子和激素  細(xì)胞膜受體  內(nèi)分泌病  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse oxytocin receptor
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. Oxytocin receptor has been reported in breast, central nervous system, heart, ovary, placenta, prostate, salivary gland, testis, uterus, and vessel.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Database links:

Entrez Gene: 281371 Cow

Entrez Gene: 5021 Human

Entrez Gene: 18430 Mouse

Entrez Gene: 397092 Pig

Entrez Gene: 25342 Rat

Omim: 167055 Human

SwissProt: P56449 Cow

SwissProt: P30559 Human

SwissProt: P97926 Mouse

SwissProt: P32306 Pig

SwissProt: P70536 Rat

SwissProt: Q28756 Sheep

Unigene: 2820 Human

Unigene: 333310 Mouse

Unigene: 6841 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

OTR在人的子宮平滑肌細(xì)胞膜上有縮宮素受體,縮宮素引起子宮收縮的機(jī)制可能是通過(guò)激活縮宮素受體而實(shí)現(xiàn)的。經(jīng)研究發(fā)現(xiàn),縮宮素受體在外周組織和中樞神經(jīng)系統(tǒng)內(nèi)均有分布。縮宮素與不同組織、細(xì)胞上的縮宮素受體結(jié)合,通過(guò)多種信號(hào)轉(zhuǎn)導(dǎo)途徑而發(fā)揮作用。
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