產(chǎn)品編號(hào) | bs-48017P |
英文名稱 | Recombinant human BMP-7 protein (Active, HEK293) |
中文名稱 | 重組人骨形態(tài)發(fā)生蛋白-7 (活性的, Tag free) |
別 名 | rhBMP-7; Bone morphogenetic protein 7 precursor; osteogenic protein 1; BMP7; OP-1; BMP 7; Bone morphogenic protein 7; Eptotermin alfa; OP 1; OP1; BMP7_HUMAN. ;Recombinant human BMP-7 protein (Active, HEK293) 人骨形態(tài)發(fā)生蛋白-7重組蛋白; 重組人骨形態(tài)發(fā)生蛋白-7; 人重組骨形態(tài)發(fā)生蛋白-7; 重組人BMP7; |
檢測(cè)分子量 | 30-38 |
性 狀 | Lyophilized |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 293-431/431 |
純 度 | >95% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | <0.5 EU/μg as determined by LAL. |
表達(dá)系統(tǒng) | HEK293 cell |
活性 | Yes |
標(biāo)簽 | Tag free |
緩 沖 液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存條件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after r |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Bone morphogenetic protein 7 (BMP-7), also known as osteogenic protein 1 (OP1) is a member of transforming growth factor β family that includes more than 20 structurally related bone growth factors. BMP-7 plays an important role in cartilage and bone formation. It also plays a role in calcium regulation and kidney development. Mature human BMP-7 is usually a homodimer consisting of two antiparallel monomers of 139 amino acids. Dimerization is facilitated by a disulfide bridge formed between the monomer, which contains three intrachain disulfide bridges arranged in a cystine knot motif. This recombinant human BMP-7 is produced by human cells.(Tag free) Biological activity: The activity was measured by its ability to induce alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line). Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. SWISS: P18075 Gene ID: 655 |
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