| 產(chǎn)品編號 | bs-21162R |
| 英文名稱 | RASGEF1B Rabbit pAb |
| 中文名稱 | RASGEF1B蛋白抗體 |
| 別 名 | GPIG4. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Pig,Sheep,Cow) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 55 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RASGEF1B: 1-100/473 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
RASGEF1B (RasGEF Domain Family Member 1B) is a Protein Coding gene. Diseases associated with RASGEF1B include Chromosome 4Q21 Deletion Syndrome. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RASGEF1C. Function: Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro). Subunit: Interacts with Ras family proteins (By similarity). Interacts with CCDC124 during cytokinesis. DISEASE: Up-regulated in macrophages stimulated with IFNG, GPI-mucins or bacterial lipopolysaccharides (LPS). Similarity: Contains 1 N-terminal Ras-GEF domain. Contains 1 Ras-GEF domain. SWISS: Q0VAM2 Gene ID: 153020 Database links: Entrez Gene: 153020 Human SwissProt: Q0VAM2 Human Unigene: 591696 Human |
