| 產(chǎn)品編號(hào) | bs-10783R |
| 英文名稱(chēng) | PERP/p53 apoptosis effector related to PMP22 Rabbit pAb |
| 中文名稱(chēng) | p53凋亡相關(guān)作用蛋白PMP22抗體 |
| 別 名 | KCP 1; KCP-1; KCP1; Keratinocyte associated protein 1; Keratinocyte-associated protein 1; Keratinocytes associated protein 1; KRTCAP 1; KRTCAP1; p53 apoptosis effector related to PMP 22; p53 apoptosis effector related to PMP-22; p53 apoptosis effector related to PMP22; P53 induced protein PIGPC1; P53-induced protein PIGPC1; Perp; PERP TP53 apoptosis effector; PERP_HUMAN; PIGPC 1; PIGPC1; THW antibody TP53 apoptosis effector; Transmembrane protein THW. |
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Specific References (1) | bs-10783R has been referenced in 1 publications.
[IF=6.575] Qiyu Gan. et al. Prognostic Value and Immune Infiltration of HPV-Related Genes in the Immune Microenvironment of Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma. CANCERS. 2023 Jan;15(5):1419 IHC ; Human.
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| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 細(xì)胞骨架 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 21 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human p53 apoptosis effector related to PMP22: 101-193/193 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
PERP (PERP, TP53 Apoptosis Effector) is a Protein Coding gene. Diseases associated with PERP include Arrhythmogenic Right Ventricular Cardiomyopathy and Uveal Melanoma. Among its related pathways are Keratinization and p53 Pathway (RnD). An important paralog of this gene is TMEM47. Function: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway. Subcellular Location: Cell junction, desmosome. Cell membrane; Multi-pass membrane protein. Note=Associated with desmosomes. Tissue Specificity: Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts. Similarity: Belongs to the TMEM47 family. SWISS: Q96FX8 Gene ID: 64065 Database links: Entrez Gene: 64065 Human Entrez Gene: 64058 Mouse Omim: 609301 Human SwissProt: Q96FX8 Human SwissProt: Q9JK95 Mouse Unigene: 201446 Human Unigene: 28209 Mouse |
