| 產(chǎn)品編號(hào) | bs-12151R |
| 英文名稱 | Rabbit Anti-NAV3 antibody |
| 中文名稱 | 神經(jīng)元引導(dǎo)蛋白3抗體 |
| 別 名 | KIAA0938; NAV 3; NAV3; NAV3_HUMAN; Neuron navigator 3; POMFIL1; Pore membrane and/or filament-interacting-like protein 1; Steerin 3; Steerin-3; STEERIN3; Unc 53 homolog 3; Unc-53 homolog 3; unc53H3. |
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Specific References (1) | bs-12151R has been referenced in 1 publications.
[IF=24.633] Yanxin Li. et al. Decoding the temporal and regional specification of microglia in the developing human brain. Cell Stem Cell. 2022 Mar;: IF ; Mouse,Human.
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| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Sheep,Chicken,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 255kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NAV3: 301-400/2385 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
May regulate IL2 production by T-cells. May be involved in neuron regeneration. Function: May regulate IL2 production by T-cells. May be involved in neuron regeneration. Subcellular Location: Nucleus outer membrane. Tissue Specificity: Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma. DISEASE: Note=A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation t(12;18)(q21;q21.2). Similarity: Sequence similarities; Belongs to the Nav/unc-53 family. Contains 1 CH (calponin-homology) domain. SWISS: Q8IVL0 Gene ID: 89795 Database links: Entrez Gene: 89795 Human Entrez Gene: 260315 Mouse Omim: 611629 Human SwissProt: Q8IVL0 Human SwissProt: Q80TN7 Mouse Unigene: 655301 Human Unigene: 225050 Mouse Unigene: 394160 Mouse Unigene: 461280 Mouse |
| 產(chǎn)品圖片 |
Sample:
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti- NAV3 (bs-12151R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 255 kD
Observed band size: 255 kD
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