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SEMA4G Rabbit pAb (bs-11479R)  
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產(chǎn)品編號(hào) bs-11479R
英文名稱 SEMA4G Rabbit pAb
中文名稱 跨膜蛋白SEMA4G抗體
別    名 SEM4G_HUMAN; sema domain immunoglobulin domain(Ig) transmembrane domain(TM) and short cytoplasmic domain(semaphorin) 4G; Sema4g; semaphorin 4G; Semaphorin 4G precursor; Semaphorin-4G.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞膜蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 90 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEMA4G: 71-120/838 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4G (semaphorin-4G) is an 838 amino acid single-pass type I membrane protein that is thought to play a role in axon guidance. Existing as three alternatively spliced isoforms, SEMA4G contains one Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a single SEMA domain.

Function:
Cell surface receptor for PLXNB2. May play a role in axon guidance.

Subunit:
Interacts with PLXNB2

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the semaphorin family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 PSI domain.
Contains 1 Sema domain.

SWISS:
Q9NTN9

Gene ID:
57715

Database links:

Entrez Gene: 57715 Human

SwissProt: Q9NTN9 Human

Unigene: 591923 Human

Unigene: 735152 Human



產(chǎn)品圖片
Sample: HepG2(Human) Cell Lysate at 30 ug A549(Human) Cell Lysate at 30 ug Primary: Anti- SEMA4G (bs-11479R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 90 kD Observed band size: 105kD
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