產(chǎn)品編號 | bs-0369M-FITC |
英文名稱 | Mouse Anti-Rabbit IgM antibody |
中文名稱 | FITC標(biāo)記的小鼠抗兔IgM |
別 名 | Mouse Anti-Rabbit IgM (FITC); Immunoglobulin M; |
Specific References (5) | bs-0369M-FITC has been referenced in 5 publications.
[IF=6.196] Cheng He. et al. Crosstalk of renal cell carcinoma cells and tumor-associated macrophages aggravates tumor progression by modulating muscleblind-like protein 2/B-cell lymphoma 2/beclin 1-mediated autophagy. CYTOTHERAPY. 2022 Oct;: IF ; Human.
[IF=5.719] Lingzi Feng. et al. A Closed-Loop Autologous Erythrocyte-Mediated Delivery Platform for Diabetic Nephropathy Therapy. NANOMATERIALS-BASEL. 2022 Jan;12(20):3556 FC ; Rabbit.
[IF=5.636] Feng JT et al. Stiffness heterogeneity-induced double-edged sword behaviors of carcinoma-associated fibroblasts in antitumor therapy. SCIENCE CHINA Materials. 2019 Jan. ICF ; Rabbit.
[IF=4.861] Fei Qi. et al. LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathway. EPIGENETICS-US. 2023;18(1):Article: 2195305 ICC ; Rat.
[IF=2.626] Zhao, Gang. et al. LINC02381, a sponge of miR-21, weakens osteogenic differentiation of hUC-MSCs through KLF12-mediated Wnt4 transcriptional repression. 2021 Nov 15 IF ; Human.
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抗體來源 | Mouse |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rabbit |
產(chǎn)品應(yīng)用 | Flow-Cyt=1:100-1000,IF=1:100-1000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
性 狀 | Liquid |
濃 度 | 2.0 mg/ml |
免 疫 原 | Native Rabbit IgM |
亞 型 | IgG |
純化方法 | affinity purified by Protein G |
緩 沖 液 | 10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol. |
保存條件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Immunoglobulin M (IgM) normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |